Meropenem renal dosing books

As the field moves forward so also do the therapeutic opportunities, and pitfalls. Optimization of meropenem dosage in the critically ill population based on renal function. The renal drug handbook the st georges hospital, adult critical. Medscape infection dosing for merrem iv meropenem, frequencybased adverse. Pharmacokinetic and pharmacodynamic properties of meropenem. The renal drug database the ultimate prescribing guide for renal practitioners. Drug dosing adjustments in patients with chronic kidney. Renal adjustment next for example, meropenem 1g iv q8hr is ordered for a septic patient with crcl of 30mlmin 1. Includes dosages for skin and structure infection, intraabdominal infection, nosocomial pneumonia and more.

The information on dosage adjustments in renal impairment given in this book is based on cockcroftgault creatinine clearance and not egfr, since the majority. Change frequency from q8h to tid when applicable iii. By continuing to browse this site you are agreeing to our use of cookies. The information on dosage adjustments in renal impairment given in this book is based on. No fetal toxicity or malformations were observed in pregnant rats and cynomolgus monkeys administered intravenous meropenem during organogenesis at doses up to 2. Renal dosage adjustment as delineated in the renal dosage adjustment policy for the respective antibiotics adjustment should be as follows. Pharmacokinetics of meropenem in patients with various degrees of. Merrem iv meropenem dosing, indications, interactions. Deshpande p, chen j, gofran a, murea m, golestaneh l. Merrem iv meropenem dosing, indications, interactions, adverse. Detailed meropenem dosage information for adults and children. An example is meropenem, where the average concentration is the target concentration of 8 to 16 mgl 8. The pharmacokinetics of meropenem were studied after intravenous infusion in patients grouped according to the impairment of their renal function. Meropenem drug monograph pediatric care online aap point.

The recommended dose of merrem iv is 500 mg given every 8 hours for skin and skin structure infections and 1 gram given every 8 hours for intraabdominal infections. Munar, pharmd, bcps, and harleen singh, pharmd oregon state university college of. Pediatric drugs analgesics antihypertensive and cardiovascular agents antimicrobial agents miscellaneous agents sedatives, hypnotics, and other drugs used in psychiatry. Abacavir abacavir lamivudine abacavir lamivudine zidovudine acarbose acebutolol acetaminophen acetazolamide acetohexamide acetohydroxamic acid acetylsalicylic acid aspirin acrivastine acyclovir adefovir adenosine albuterol inhaled albuterol oral alfentanil alfentanil allopurinol alprazolam alteplase tissuetype plasminogen activator. Drug dosing adjustments in patients with chronic kidney disease myrna y. If unable to dose stagger, may revert to traditional infusion 4. No dosage adjustments except those related to renal impairment. For pediatric patients weighing over 50 kg administer merrem iv at a dose of 500 mg every 8 hours for csssi, 1 gram every 8 hours for ciai and 2 grams every 8 hours for meningitis. Meropenem removal in critically ill patients undergoing sustained lowefficiency dialysis sled. When treating complicated skin and skin structure infections caused by p. Meropenem reference guide for safe and effective use from the american society of. Thrombocytopenia has been reported in patients with renal impairment.